At Bespoke Dentistry and Aesthetics in Del Mar, CA, we’re redefining what it means to care for your skin. Our team is passionate about providing innovative, results-driven treatments that are as comfortable as they are effective—without the need for needles, injections, or extended recovery.
We’re proud to introduce one of the newest advancements in regenerative aesthetics: Platelet-Rich Fibrin Matrix (PRFM)—a more effective evolution of PRP and PRF therapies, designed to amplify your skin’s natural healing abilities. Whether you’re preparing for an event, enhancing your post-cleaning glow, or looking for a long-term anti-aging solution, PRFM microneedling is a beautiful, natural option—customized just for you.
“Our mantra here is no pain, no sensitivity, making it seamless, and really caring for you in a bespoke or customized manner—while ensuring you receive great results at the same time.”
— Ryan Stenfl, CEO of Bespoke Dentistry and Aesthetics
What Is PRFM—and How Is It Different from PRP or PRF?
You may already be familiar with Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF), two powerful regenerative treatments that use your own blood to stimulate healing, collagen production, and skin cell turnover. But now, there’s something even better: Platelet-Rich Fibrin Matrix (PRFM).
PRFM takes the healing potential of PRP and PRF to the next level by creating a structured matrix or lattice that holds your body’s natural growth factors in place for longer. This means your skin cells stay in contact with those powerful nutrients for more time—leading to deeper healing, greater absorption, and longer-lasting results.
“This lattice is creating a matrix where it’s going to support healing with your own body’s nutrients, but unlike traditional plasma, it doesn’t just run off. It stays and bathes the skin.”
Here’s how it works:
- A small sample of your blood is taken—just like a basic blood draw.
- The blood is placed in a special vial and spun in our CellFill centrifuge system, separating out the beneficial platelets and fibrin.
- Additional components in the vial transform the fibrin into a matrix, forming a gel-like consistency that holds in place on your skin.
- This matrix is applied to your skin—either post-microneedling or during an injection—where it continues delivering nutrients long after your appointment ends.
Best of all? PRFM is included at no additional cost during qualifying microneedling or injection appointments at Bespoke.
Why PRFM Is a Game-Changer for Skin Rejuvenation
One of the challenges with traditional PRP is that once it’s applied to the skin, it absorbs quickly or runs off, giving it only a brief window of effectiveness. PRFM, on the other hand, is designed to stay in place and support your skin cells longer.
“The most important thing with PRFM is that the matrix is going to sit and bathe those cells. It increases the surface area and contact time—delivering better, longer-lasting results.”
That extra time makes all the difference. Your skin cells are able to absorb more of your body’s natural nutrients, accelerating their repair cycle and promoting firmer, brighter, more youthful skin—naturally.
The PRFM matrix also provides an ideal solution for patients with sensitive skin or who prefer a more natural alternative to fillers or harsh chemicals. Since it’s created from your own body, there’s zero risk of reaction, rejection, or foreign substances.
The Bespoke Microneedling Experience
Microneedling is one of the most popular anti-aging treatments available—and for good reason. It works by creating thousands of controlled “micro-traumas” to the skin, which stimulate your body’s natural healing response, ramping up collagen production and helping your skin rebuild stronger, smoother, and more evenly toned.
Think of it like working out: small tears in the muscle fiber during exercise make your muscles stronger as they heal. Microneedling does the same for your skin.
“When we create these micro traumas through microneedling and then coat it in your blood, those nutrients enter the skin and stimulate a framework for stronger, smoother, more youthful skin.”
At Bespoke, we use the InoPen, a powerful, precise, and comfortable microneedling device. Our approach is 100% customizable, so whether you prefer a light touch or deeper rejuvenation, we’ll tailor the treatment to your skin’s unique needs.
Before your session, we’ll apply a numbing cream—unless you prefer to skip it—and walk you through what to expect. During the treatment, our skilled nurses move systematically across the skin, ensuring full coverage and consistency.
Afterward, we apply your PRFM matrix directly onto the freshly treated skin. The result? Your skin drinks in your body’s healing nutrients exactly where it needs them most—leading to faster recovery and enhanced results.
Why Patients Love It
Patients choose our PRFM microneedling treatments for:
- Improved texture and tone
- Reduction in fine lines and wrinkles
- Fewer breakouts and clogged pores
- Brighter, tighter, more youthful skin
- Long-lasting results with minimal downtime
Most patients experience only mild redness or sensitivity for a day or two—and many feel comfortable going out the same day. It’s the perfect option if you want real results, without having to put your life on pause.
